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 Cinchona  Pitayensis  must  also  be  referred  to  C.  officinalis  as  a  
 variety.  This  attains  a height  of  60  feet  and  furnishes  also a  
 portion  of the  Pitaya-bark.  I t  is this particular cinchona, which  
 in Upper  India  yielded  in  some  instances  the very large quantity  
 of  11  per  cent,  alkaloids,  nearly  6  per  cent,  quinin,  the  rest  
 quinidin  and  cinchonin ;  this  plant  is  now  annihilated  for  bark-  
 purposes  in  its  native  forests. 
 Cinchonas  raised  from  seeds  provided  by  the writer  of  this work,  
 have withstood  the  slight  frosts  at  San  Francisco  [G.  P .  Rixford]. 
 Tlie Uritusinga-  or  Loxa-variety  grows  in  its  native  forests  to a  
 height  of  60  feet  and more  [Pavon]  and attained  in  Ceylon  in fifteen  
 years  a  height  of  28  feet, with  a  stem-girth  of  nearly  2  feet.  The  
 price  of its  bark  in  1879  was  about  7s.  per  lb.,  and  of renewed  bark  
 11s.  Mr.  Molvor  obtained  6,850  cuttings  from  one  imported plant  
 in  twenty months ;  but  all  Cinchonse  produce seeds  copiously,  so that  
 the  raising  of  great  numbers  of plants  can  be  effected with  remarkable  
 facility.  The bark has  yielded  7'4  to  lO'O  per  cent,  sulphate  of  
 quinin  [Howard]. 
 In  J a v a   some  of  the  best  results  were  obtained  with  Cinchona  
 Hasskarliana,  Miq., a species  seemingly as yet not critically identified.  
 Cinchona-seeds  do  not  long  retain  their vitality;  but  as  they  are  so  
 very  light,  no  difficulty  exists  in  sending  them  speedily  even  to  
 widely  distant  places. 
 C in c h o n a   s u c o i r u b r a ,   Pavon.* 
 Middle Andine  regions  of  Peru  and  Ecuador.  A  tree,  attaining  a  
 height  of  40  feet,  yielding  the Red  Peru-bark,  rich  in  cinchonin  and  
 cinchonidin.  I t  is  this  species, which is  predominantly  cultivated  on  
 the  mountains  of  Bengal.  In  India  it  thrives  a t  lower  elevations  
 than  other Cinchonas,  proves  of  quicker growth, and there  tlie mixed  
 cheap  Cinchona-alkaloids  forming  the  “ Quinettum ”  are  largely  
 derived from  this  plant  [G.  King,  J . S. Gamble],  I t   has  been  found  
 hardy  iu  Lower Gippsland  and  the Westernport-district  of Victoria.  
 I t   grew  in  Madeira  a t  an  elevation  of  500  feet,  after  having  been  
 planted  two  and  a  half years,  to  a  height  of 20  feet,  flowering  freely  
 also.  All  these  Cinchonas  promise  to  become  of  importance  for  
 culture  iu  the warmest  regions  of extra-tropical  countries,  on  places  
 not  readily  accessible  or  eligible  for  cereal  culture.  The Peruvian  
 proverb, th a t  Cinchona-trees like  to  be  “ within  sight  of  snow,” gives  
 some  clue  to  the  conditions  under  which  they  thrive  best.  They  
 delight  in  the  shelter  of  forests,  where  there  is  an  equable  temperature, 
   no  frost,  some  humidity  a t  all  times  both  in  air  and  soil, where  
 the  ground is  deep  and  largely  consists  of  the  remnants  of  decayed  
 vegetable  substances,  and where  the  subsoil is  open.  Drippage  from  
 shelter-trees  too  near will  be  hurtful  to  tlie  plants.  Closed  valleys  
 and  deep  gorges,  into  which  cold  air  will  sink,  are  also  not  well  
 adapted  for  Cinchona-cnlture.  The  Cinchona-region  may  be  regarded  
 as  inter-jacent  between  the  coffee-  and  the  tea-region,  or 
 nearly  coinciding  with  th a t  of  the  Assam-tea.  Cross  found  the  
 temperature  of some  of  the  best  natural  Cinchona-regions to fluctuate  
 between  35°  and  60°  F.  We  here  ought  to consociate  the  Peru-bark  
 plants with  naturally  growing  fern-trees,  but  only  in  the warmest  
 valleys  and  richest soil.  The  best temperature for Cinchonas  is  from  
 53°  to  66°  P .;  but  for  the most  part  they  will  endure  in  open  places  
 a minimum  of  32°  F .;  in  the  brush-shades  of  the Botanic Garden  of  
 Melbourne, where  already many years  ago  Cinchonas were  raised  by  
 the  thousands,  they have  even  resisted  uninjured  a  temperature  of  a  
 few degrees  less, wherever  the wind had no  access, while  under  such  
 very  slight  cover  the Cinchonas withstood also a heat of a few degrees  
 over  100°  F. 
 The  plants  are most  easily  raised  from  seed,  best  under  some cover  
 such  as mats ;  they produce seeds copiously some  years after planting.  
 C.  sucoirubra,  first  introduced  into  California  by  the  writer  of  this  
 work  together with  the  principal  other  species,  thrives  well  in  the  
 lower ooast-ranges  as  far  north  as  San  Francisco  ;  better indeed  than  
 C.  Calisaya,  according  to  Dr.  Herman Behr.  The  quantity  of  alk aloids  
 in  the  bark  can  be much  increased  by  artificial  treatment,  if the  
 bark  is  only  removed to  about  one-third  on  one  side  of  the  stem  and  
 the denuded  part  covered with  moss  or  straw-matting  (kept moist),  
 under which  in one  year  as much  bark  is formed  as otherwise requires  
 three  years’  growth—such  forced  bark  moreover  containing  the  
 astounding  quantity  of  25  per  cent,  alkaloids,  because  no  loss  of  
 these  precious  substances  takes  place  by  gradual  disintegration  
 through age.  The root-bark of  some Cinchonas has proved  to contain  
 as much  as  8  per  cent,  of  alkaloids  (see  Gardeners’  Chronicle,  1877,  
 p.  212).  The  income  from  Java-plantations  is  considerably  over  
 double  the cost  of the  expenses of  culture  and transit,  Mr. Howard’s  
 opinion,  th a t  Cinchonas  in  lowland-plantations  produce  a  far  less  
 quantity  of alkaloids,  needs  further  confirmation,  particularly  regarding  
 the valuable  quinin  and  cinchonidin  ;  probably  however  geologic  
 conditions  have  in  all  instances to  be  taken  into  account  also. 
 Yonng  Cinchona-plants  are  set  out  at  distances  of  about  6  feet.  
 The  harvest  of  bark  begins  in  the  fourth  or  fifth  year.  The  price  
 varies in  Europe  from  2s.  to  9s.  per  lb.  according  to  quality.  The  
 limits  assigned  to  this  literary  compilation  do  not  admit  of  entering  
 further  into  details  on  this  occasion  ;  but  I   may  add,  th a t  iu  the  
 Darjeeling-district over three millions of Cinchona-plants were already  
 in  cultivation  during  1869  in  Government-plantations.  Cultivation  
 of  Cinchona  for  commercial  purposes  was  first  initiated  in  J a v a   
 through  Dr.  Hasskarl  in  1851  at  the  suggestion  and  under  the  
 direction of Professor Miquel  ;  but  240,000 lbs.  of bark were  already  
 exported  from  this  island  in  1880.  The  British  harvest  in  the  
 Madras-Presidenoy alone amounted to  150,000 lbs.  in  1875.  Brigade-  
 Surgeoii  Dr.  G.  King  reports  in  1880,  th a t  four  million  trees  of  
 Cinchona  sucoirubra are  now  under his  control  in  the  Sikkim-planta-  
 tions.  This  has  proved  the  hardiest  species  ;  it  grows  under  a wide  
 range  of  conditions  and  seeds  freely  ;  thus  it  is  the  most  valuable 
 s